Subgingival sustained-release product containing the antibiotic minocycline hydrochloride incorporated into a bioresorbable polymer, poly (glycolide-co-di-lactide) or PGLA, for profesional subgingival administrtion into periodontal pockets. Each unit-dose cartridge delivers 1 mg minocycline hydrocholride. Cartridge must be used in application handle (sold seperatly) for product administration. Indicated as an adjunct to scaling and root-planing procedures for reduction of pocket depth in patients with adult periodontitis.